A History of Science-4 [35]
digested after death was written by Hunter at the desire of Sir John Pringle, when he was president of the Royal Society, and the circumstance which led to this is as follows: "I was opening, in his presence, the body of a patient of his own, where the stomach was in part dissolved, which appeared to him very unaccountable, as there had been no previous symptom that could have led him to suspect any disease in the stomach. I took that opportunity of giving him my ideas respecting it, and told him that I had long been making experiments on digestion, and considered this as one of the facts which proved a converting power in the gastric juice. . . . There are a great many powers in nature which the living principle does not enable the animal matter, with which it is combined, to resist--viz., the mechanical and most of the strongest chemical solvents. It renders it, however, capable of resisting the powers of fermentation, digestion, and perhaps several others, which are well known to act on the same matter when deprived of the living principle and entirely to decompose it. "
Hunter concludes his paper with the following paragraph: "These appearances throw considerable light on the principle of digestion, and show that it is neither a mechanical power, nor contractions of the stomach, nor heat, but something secreted in the coats of the stomach, and thrown into its cavity, which there animalizes the food or assimilates it to the nature of the blood. The power of this juice is confined or limited to certain substances, especially of the vegetable and animal kingdoms; and although this menstruum is capable of acting independently of the stomach, yet it is indebted to that viscus for its continuance.[5]
THE FUNCTION OF RESPIRATION
It is a curious commentary on the crude notions of mechanics of previous generations that it should have been necessary to prove by experiment that the thin, almost membranous stomach of a mammal has not the power to pulverize, by mere attrition, the foods that are taken into it. However, the proof was now for the first time forthcoming, and the question of the general character of the function of digestion was forever set at rest. Almost simultaneously with this great advance, corresponding progress was made in an allied field: the mysteries of respiration were at last cleared up, thanks to the new knowledge of chemistry. The solution of the problem followed almost as a matter of course upon the advances of that science in the latter part of the century. Hitherto no one since Mayow, of the previous century, whose flash of insight had been strangely overlooked and forgotten, had even vaguely surmised the true function of the lungs. The great Boerhaave had supposed that respiration is chiefly important as an aid to the circulation of the blood; his great pupil, Haller, had believed to the day of his death in 1777 that the main purpose of the function is to form the voice. No genius could hope to fathom the mystery of the lungs so long as air was supposed to be a simple element, serving a mere mechanical purpose in the economy of the earth.
But the discovery of oxygen gave the clew, and very soon all the chemists were testing the air that came from the lungs--Dr. Priestley, as usual, being in the van. His initial experiments were made in 1777, and from the outset the problem was as good as solved. Other experimenters confirmed his results in all their essentials--notably Scheele and Lavoisier and Spallanzani and Davy. It was clearly established that there is chemical action in the contact of the air with the tissue of the lungs; that some of the oxygen of the air disappears, and that carbonic-acid gas is added to the inspired air. It was shown, too, that the blood, having come in contact with the air, is changed from black to red in color. These essentials were not in dispute from the first. But as to just what chemical changes caused these results was the subject of controversy. Whether, for example, oxygen is actually absorbed into the blood, or whether it merely unites with carbon
Hunter concludes his paper with the following paragraph: "These appearances throw considerable light on the principle of digestion, and show that it is neither a mechanical power, nor contractions of the stomach, nor heat, but something secreted in the coats of the stomach, and thrown into its cavity, which there animalizes the food or assimilates it to the nature of the blood. The power of this juice is confined or limited to certain substances, especially of the vegetable and animal kingdoms; and although this menstruum is capable of acting independently of the stomach, yet it is indebted to that viscus for its continuance.[5]
THE FUNCTION OF RESPIRATION
It is a curious commentary on the crude notions of mechanics of previous generations that it should have been necessary to prove by experiment that the thin, almost membranous stomach of a mammal has not the power to pulverize, by mere attrition, the foods that are taken into it. However, the proof was now for the first time forthcoming, and the question of the general character of the function of digestion was forever set at rest. Almost simultaneously with this great advance, corresponding progress was made in an allied field: the mysteries of respiration were at last cleared up, thanks to the new knowledge of chemistry. The solution of the problem followed almost as a matter of course upon the advances of that science in the latter part of the century. Hitherto no one since Mayow, of the previous century, whose flash of insight had been strangely overlooked and forgotten, had even vaguely surmised the true function of the lungs. The great Boerhaave had supposed that respiration is chiefly important as an aid to the circulation of the blood; his great pupil, Haller, had believed to the day of his death in 1777 that the main purpose of the function is to form the voice. No genius could hope to fathom the mystery of the lungs so long as air was supposed to be a simple element, serving a mere mechanical purpose in the economy of the earth.
But the discovery of oxygen gave the clew, and very soon all the chemists were testing the air that came from the lungs--Dr. Priestley, as usual, being in the van. His initial experiments were made in 1777, and from the outset the problem was as good as solved. Other experimenters confirmed his results in all their essentials--notably Scheele and Lavoisier and Spallanzani and Davy. It was clearly established that there is chemical action in the contact of the air with the tissue of the lungs; that some of the oxygen of the air disappears, and that carbonic-acid gas is added to the inspired air. It was shown, too, that the blood, having come in contact with the air, is changed from black to red in color. These essentials were not in dispute from the first. But as to just what chemical changes caused these results was the subject of controversy. Whether, for example, oxygen is actually absorbed into the blood, or whether it merely unites with carbon