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A History of Science-4 [43]

By Root 1626 0
the time, also gave attention to the problem of improving the microscope, and in 1821 he introduced what was called an aplanatic combination of lenses, in which, as the name implies, the spherical aberration was largely done away with. It was thought that the use of this Herschel aplanatic combination as an eyepiece, combined with the Wollaston doublet for the objective, came as near perfection as the compound microscope was likely soon to come. But in reality the instrument thus constructed, though doubtless superior to any predecessor, was so defective that for practical purposes the simple microscope, such as the doublet or the Coddington, was preferable to the more complicated one.

Many opticians, indeed, quite despaired of ever being able to make a satisfactory refracting compound microscope, and some of them had taken up anew Sir Isaac Newton's suggestion in reference to a reflecting microscope. In particular, Professor Giovanni Battista Amici, a very famous mathematician and practical optician of Modena, succeeded in constructing a reflecting microscope which was said to be superior to any compound microscope of the time, though the events of the ensuing years were destined to rob it of all but historical value. For there were others, fortunately, who did not despair of the possibilities of the refracting microscope, and their efforts were destined before long to be crowned with a degree of success not even dreamed of by any preceding generation.

The man to whom chief credit is due for directing those final steps that made the compound microscope a practical implement instead of a scientific toy was the English amateur optician Joseph Jackson Lister. Combining mathematical knowledge with mechanical ingenuity, and having the practical aid of the celebrated optician Tulley, he devised formulae for the combination of lenses of crown glass with others of flint glass, so adjusted that the refractive errors of one were corrected or compensated by the other, with the result of producing lenses of hitherto unequalled powers of definition; lenses capable of showing an image highly magnified, yet relatively free from those distortions and fringes of color that had heretofore been so disastrous to true interpretation of magnified structures.

Lister had begun his studies of the lens in 1824, but it was not until 1830 that he contributed to the Royal Society the famous paper detailing his theories and experiments. Soon after this various continental opticians who had long been working along similar lines took the matter up, and their expositions, in particular that of Amici, introduced the improved compound microscope to the attention of microscopists everywhere. And it required but the most casual trial to convince the experienced observers that a new implement of scientific research had been placed in their hands which carried them a long step nearer the observation of the intimate physical processes which lie at the foundation of vital phenomena. For the physiologist this perfection of the compound microscope had the same significance that the, discovery of America had for the fifteenth-century geographers--it promised a veritable world of utterly novel revelations. Nor was the fulfilment of that promise long delayed.

Indeed, so numerous and so important were the discoveries now made in the realm of minute anatomy that the rise of histology to the rank of an independent science may be said to date from this period. Hitherto, ever since the discovery of magnifying-glasses, there had been here and there a man, such as Leuwenhoek or Malpighi, gifted with exceptional vision, and perhaps unusually happy in his conjectures, who made important contributions to the knowledge of the minute structure of organic tissues; but now of a sudden it became possible for the veriest tyro to confirm or refute the laborious observations of these pioneers, while the skilled observer could step easily beyond the barriers of vision that hitherto were quite impassable. And so, naturally enough, the physiologists of the fourth decade
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