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Island - Aldous Huxley [157]

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a committed social being—how to escape from the prison bars of self and the pressures of here and now into realms of pure goodness and pure enjoyment.”

“‘One of Aldous’s major preoccupations was how to achieve self-transcendence while yet remaining a committed social being.’”

Huxley pursued his quest for “pure goodness and pure enjoyment” right up to the end of his life on November 22, 1963. Today he is remembered as one of the great explorers of twentieth-century literature, a writer who continually reinvented himself as he pushed his way deeper and deeper into the mysteries of human consciousness.

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About the book

Mind at Large

by Aldous Huxley

Chapter 15 of Island describes Will Faranby’s experience with the mind-expanding “moksha-medicine.” Here in this excerpt from his classic nonfiction work The Doors of Perception, Aldous Huxley explains his own fascination with psychedelics—and his first experience with the drug mescalin.

IT WAS IN 1886 that the German pharmacologist, Ludwig Lewin, published the first systematic study of the cactus, to which his own name was subsequently given. Anhalonium Lewinii was new to science. To primitive religion and the Indians of Mexico and the American Southwest it was a friend of immemorially long standing. Indeed, it was much more than a friend. In the words of one of the early Spanish visitors to the New World, “they eat a root which they call peyote, and which they venerate as though it were a deity.”

Why they should have venerated it as a deity became apparent when such eminent psychologists as Jaensch, Havelock Ellis and Weir Mitchell began their experiments with mescalin, the active principle of peyote. True, they stopped short at a point well this side of idolatry; but all concurred in assigning to mescalin a position among drugs of unique distinction. Administered in suitable doses, it changes the quality of consciousness more profoundly and yet is less toxic than any other substance in the pharmacologist’s repertory.

Mescalin research has been going on sporadically ever since the days of Lewin and Havelock Ellis. Chemists have not merely isolated the alkaloid; they have learned how to synthesize it, so that the supply no longer depends on the sparse and intermittent crop of a desert cactus. Alienists have dosed themselves with mescalin in the hope thereby of coming to a better, a first-hand, understanding of their patients’ mental processes. Working unfortunately upon too few subjects within too narrow a range of circumstances, psychologists have observed and catalogued some of the drug’s more striking effects. Neurologists and physiologists have found out something about the mechanism of its action upon the central nervous system. And at least one professional philosopher has taken mescalin for the light it may throw on such ancient, unsolved riddles as the place of mind in nature and the relationship between brain and consciousness.

There matters rested until, two or three years ago, a new and perhaps highly significant fact was observed. Actually the fact had been staring everyone in the face for several decades; but nobody, as it happened, had noticed it until a young English psychiatrist, at present working in Canada, was struck by the close similarity, in chemical composition, between mescalin and adrenalin. Further research revealed that lysergic acid, an extremely potent hallucinogen derived from ergot, has a structural biochemical relationship to the others. Then came the discovery that adrenochrome, which is a product of the decomposition of adrenalin, can produce many of the symptoms observed in mescalin intoxication. But adrenochrome probably occurs spontaneously in the human body. In other words, each one of us may be capable of manufacturing a chemical, minute doses of which are known to cause profound changes in consciousness. Certain of these changes are similar to those which occur in that most characteristic plague of the twentieth century, schizophrenia.

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