Merriam-Webster's Dictionary and Thesaurus - Merriam-Webster [371]
1desolate adjective 1 : DESERTED, ABANDONED
2 : joyless, disconsolate, and sorrowful through or as if through separation from a loved one : LONELY
3 : DILAPIDATED
4 : BARREN, LIFELESS
5 : devoid of warmth, comfort, or hope : CHEERLESS
— des·o·late·ly adverb
— des·o·late·ness noun
Synonyms
[2] forlorn, lonely, lonesome—more at LONESOME
[5] bleak, cheerless, dismal, dreary, gloomy, glum, gray, miserable, wretched
2desolate verb -lat·ed; -lat·ing : to make desolate : destroy the activity, vitality, or sound condition or contentment of : make wretched
des·o·la·tion noun 1 : the action of desolating : state of being desolated
2 : the quality or state of being sad : SADNESS
3 : LONELINESS
4 : a condition of neglect leading to confusion and disintegration or of natural barrenness and bleakness
5 : barren wasteland
Synonyms
[1] annihilation, demolition, destruction, devastation, havoc, loss, obliteration, ruin, wastage, wreckage—more at DESTRUCTION
[4] dilapidation, disrepair, neglect—more at NEGLECT
[5] barren, desert, waste, wasteland—more at WASTELAND
des·oxy·ri·bo·nu·cle·ic acid noun : DNA
1despair verb : to lose all hope or confidence
2despair noun 1 : utter destruction of hope
2 : a cause of hopelessness
Synonyms
desperation, despondency, forlornness, hopelessness; also blues, depression, dejection, desolation, doldrums, dolor, dumps, gloom, melancholy, oppression, sadness, sorrow, unhappiness; cynicism, pessimism; acceptance, resignation
Antonyms
hope, hopefulness
de·spair·ing adjective : given to, arising from, or marked by despair : having no hope
— de·spair·ing·ly adverb
Synonyms
defeatist, hopeless, pessimistic—more at PESSIMISTIC
des·per·a·do noun, plural -does or -dos : a bold or reckless criminal
des·per·ate adjective 1 : being beyond or almost beyond hope : causing despair
2 : RASH
3 : extremely intense
— des·per·ate·ly adverb
— des·per·ate·ness noun
des·per·a·tion noun 1 : a loss of hope and surrender to despair
2 : a state of hopelessness leading to rashness
Synonyms
despair, despondency, forlornness, hopelessness—more at DESPAIR
de·spi·ca·ble adjective : deserving to be despised
— de·spi·ca·bly adverb
Synonyms
contemptible, lousy, nasty, pitiful, scabby, scurvy, sorry, wretched—more at CONTEMPTIBLE
base, contemptible, detestable, dirty, dishonorable, ignoble, low, mean, snide, sordid, vile, wretched—more at IGNOBLE
de·spise verb de·spised; de·spis·ing 1 : to look down on with contempt or aversion : DETEST
2 : to regard as negligible, worthless, or distasteful
Synonyms
[1] abhor, abominate, detest, execrate, hate, loathe—more at HATE
[2] disregard, flout, scorn—more at SCORN
1despite preposition : in spite of
Synonyms
notwithstanding, regardless of, with
2despite noun : the act of despising : CONTEMPT
de·spoil verb : to strip of belongings, possessions, or value
— de·spoil·er noun
— de·spoil·ment noun
Synonyms
loot, maraud, pillage, plunder, ransack, sack, strip—more at RANSACK
de·spo·li·a·tion noun : the act of plundering : the state of being despoiled
1despond verb : to become discouraged or disheartened
2despond noun : DESPONDENCY
de·spon·den·cy noun : the state of being despondent
Synonyms
blues, dejection, depression, desolation, doldrums, dumps, forlornness, gloom, heartsickness, melancholy, sadness—more at SADNESS
despair, desperation, forlornness, hopelessness—more at DESPAIR
de·spon·dent adjective : feeling or showing extreme discouragement, dejection, or depression
— de·spon·dent·ly adverb
Synonyms
brokenhearted, dejected, depressed, disconsolate, heartsick, miserable, sad, wretched—more at SAD
des·pot noun [ORIGIN: MF despote, fr. Gk despotēs master, lord, autocrat]
1 : a ruler with absolute power and authority
2 : a person exercising power tyrannically
Synonyms
autocrat, dictator, oppressor, tyrant; also dominator, master, overlord, ruler; king, lord, monarch, prince, queen, sovereign;