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The 4-Hour Body_ An Uncommon Guide to Ra - Timothy Ferriss [54]

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our results were “strange” relates to the “stable form” bit. Most research indicates that allicin should have almost zero bioavailability more than six days after extraction from garlic cloves, particularly after exposure to stomach acid. Our confounding results could be due to a combination of other organic components, most notably one precursor to allicin: S-Allyl cysteine (alliin). S-Allyl cysteine exhibits outstanding oral bioavailability, near 100% in large mammals.14

Until further research concludes otherwise, I suggest using an aged-garlic extract (AGE) with high allicin potential that includes all constituent parts, including S-Allyl cysteine.

I’ve tried consuming it fresh, chomping on cloves, and it isn’t kind to your digestive tract. If you are going the whole-food route, use it in your cooking to prevent stomach self-destruction.

For precision and convenience, I use supplements to reach my target baseline in dosing, and I use extra garlic in food for delectable (but not necessary) insurance above that baseline.


Warnings

Ensure adequate consumption of B-complex vitamins while using PAGG and consult your doctor before use if you have a medical condition (e.g., hypertension, hypoglycemia, diabetes) or are taking any medications. In particular, blood-thinning medications (e.g., warfarin, aspirin, etc.), thyroid medications, or anti-anxiety drugs like clozapine.

If you are pregnant or breastfeeding, do not use PAGG. Blood-thinning compounds ain’t for babies.

TOOLS AND TRICKS

I currently use the following products. I have no financial interest in any of them:

Vitamin Shoppe—Allicin 6000 Garlic, 650 mg, 100 caplets (www.fourhourbody.com/garlic)

Mega Green Tea Extract (decaffeinated), 725 mg, 100 capsules (www.fourhourbody.com/greentea)

Vitamin Shoppe—Alpha-Lipoic Acid, 300 mg, 60 capsules (www.fourhourbody.com/ala)

Nature’s Life—Policosanol, 60 tablets (www.fourhourbody.com/policosanol)

End of Chapter Notes

10. The ephedrine increases cAMP levels, the caffeine slows cAMP breakdown, and the aspirin further helps sustain increased cAMP levels by inhibiting prostagladin production.

11. In over-the-counter drugs, ephedrine is generally mixed with guafenesin (an expectorant), as it can otherwise be freebased with basic lab supplies into methamphetamine.

12. Except for those predisposed to Insulin Autoimmune Syndrome (IAS).

13. If you’re a male bodybuilder, this effect on tamoxifen can be a good thing, but watch your HDL, which can drop like a stone.

14. Though S-Allyl cysteine (SAC) is an easier molecule to get into your bloodstream and has been implicated in minimizing the damage of glycation and free radicals in diabetes, it would be premature to label this the single component responsible for lipid changes or fat-loss. The fat-loss could well be due to several synergistic compounds in garlic that activate phase I and II detoxification enzymes.

Advanced

ICE AGE

Mastering Temperature to

Manipulate Weight

Don’t tell me it’s impossible, tell me you can’t do it. Tell me it’s never been done … the only things we really know are Maxwell’s equations, the three laws of Newton, the two postulates of relativity, and the periodic table. That’s all we know that’s true. All the rest are man’s laws.

—Dean Kamen, inventor of the Segway and recipient of the National Medal of Technology and Lemelson-MIT Prize

“Michael Phelps eats 12,000 calories a day …”

That was all Ray Cronise heard from across the room. He jerked his eyes up from the spreadsheet and reached for the TiVo to pause the television.

Twelve thousand calories.

Ray Cronise had been a high-ranking material scientist at NASA for almost 15 years, and his specialties included biophysics and analytical chemistry. He’d been in mission operations and seen—hell, helped produce—research the public wouldn’t see for decades.

But spending half of his life behind a computer had taken its toll. The creeping two to four pounds per year had added up and left him weighing 230 pounds at 5′9″.

It was now a much-improved 209-pound Ray Cronise who sat with

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